Kimura Disease in Infraorbital Region of Face Manifesting with a Huge Mass Lesion: A Rare Case Report

Case Report

Ann Surg Perioper Care. 2017; 2(3): 1034.

Kimura Disease in Infraorbital Region of Face Manifesting with a Huge Mass Lesion: A Rare Case Report

Sun B1*, Zhao B2, Yu Y1, Liu K1 and Zhang W1

¹Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Changchun, P.R.China

²Department of Periodontics, School and Hospital of Stomatology, Jilin University, Changchun, P.R.China

*Corresponding author: Sun B, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Qinghua road 1500, Changchun, Jilin province, P.R.China

Received: November 19, 2017; Accepted: December 12, 2017; Published: December 19, 2017

Abstract

Kimura disease (KD) is a chronic inflammatory disorder that presents as painless or pruritic subcutaneous lesions with in the head and neck, especially in the parotid and submandibular regions. Peripheral eosinophilia and elevated serum IgE levels are the characteristics of the disease. Here, we present a case of Kimura Disease in Infraorbital region of face manifesting with a huge mass lesion.

Keywords: Kimura disease; Infraorbital region; Huge mass

Introduction

Kimura’s disease is a benign chronic condition of unknown cause, which usually presents as a painless swelling of subcutaneous tissue that develops into either single or multiple locations in the head and neck region, especially in the major salivary glands and regional lymph nodes. Other sites such as the oral cavity, axilla, extremity, trunk and groin have also been involved. Peripheral eosinophilia and elevated serum IgE levels are the characteristics of the disease [1]. Surgical resection and low dose radiotherapy are the main treatment methods. Here, we present a case of Kimura Disease in infraorbital region of face manifesting with a huge mass lesion.

Case Presentation

A 65-year-old Chinese man presented with a huge subcutaneous tissue mass lesion in right infraorbital region of face, which had been repeated growth and contraction for 20 years. Examination revealed that the mass was rubbery, painless, and surface skin of the mass was similar to the orange peel (Supplemental Figure 1). Magnetic resonance imaging (MRI) showing a huge mass with partial low signal intensity accompanied with high signal intensity septum in the right infraorbital and buccal area (T1 Short T2 inversion Recovery) (Figure 1, Supplemental Figure 2). Peripheral blood test showed that the leukocyte count was 14.2×109/L with 58% eosinophils.