Diagnosis of Familial Hypercholesterolemia Associated with Premature Coronary Disease

Case Report

Austin Cardiol. 2017; 2(1): 1006.

Diagnosis of Familial Hypercholesterolemia Associated with Premature Coronary Diseases

Freire DM¹, Geller M², Sousa Melo Costa WR¹ and Kaufman R¹*

¹Instituto Estadual de Cardiologia, Brazil

²Universidade Federal do Rio de Janeiro (UFRJ), Brazil

*Corresponding author: Renato Kaufman, Instituto Estadual de Cardiologia, Universidade do Estado do Rio de Janeiro (UERJ), Brazil

Received: October 07, 2016; Accepted: January 13, 2017; Published: January 16, 2017

Abstract

We are presenting the case of familial hypercholesterolemia, an important cause of premature and advanced coronary disease that is often misdiagnosed. In this case, we demonstrate not only the difficulty to attach the goals of lipid level, but also the importance of familial screening.

Keywords: Familial hypercholesterolemia; Coronary disease; Lipids

Case Presentation

A fifty year old man was transferred to the State Heart Institute of Rio de Janeiro (IECAC) for a coronarography after a non-ST-segment elevation myocardial infarction. He had history of hypertension and dyslipidemia since the age of 26, family history of sudden death (father at age 24) and a family history of dyslipidemia (brother and son).

During admission, an arcus corneae (Figure 1) was seen, suggesting familial hypercholesterolemia. The coronarography showed trivascular disease with 90% obstruction in medium LAD, proximal 80% in Cx and 99% proximal in right coronary artery. Because of the coronary anatomy a coronary bypass surgery was indicated.

Citation:Freire DM, Geller MSousa Melo Costa WR and Kaufman R. Diagnosis of Familial Hypercholesterolemia Associated with Premature Coronary Disease. Austin Cardiol. 2017; 2(1): 1006.