Correlation between Diabetic Macular Edema and Peripheral Retinal Ischemia in Saudi Arabia

Research Article

Austin J Clin Ophthalmol. 2015; 2(5): 1058.

Correlation between Diabetic Macular Edema and Peripheral Retinal Ischemia in Saudi Arabia

Al Shammari AS¹ and El-Agamy AF²*

¹Department of Optometry and Vision Sciences, College of Applied Medical Sciences, King Saud University, Saudi Arabia

²Department of Optometry and Vision Sciences, College of Applied Medical Sciences, King Saud University, Saudi Arabia and Faculty of Medicine, Mansoura University, Egypt

*Corresponding author: El-Agamy AF, Department of Optometry and Vision Sciences, College of Applied Medical Sciences (female section), King Saud University, Building 11, Third Floor, Office 223, Riyadh, Saudi Arabia

Received: August 19, 2015; Accepted: October 01, 2015; Published: October 08, 2015

Abstract

Evaluation of the correlation between Peripheral Retinal Ischemia (PRI) and Diabetic Macular Edema (DME)in Saudi patients using Ultra-Wide Field Fluorescein Angiography (UWFA) and Spectral domain Optical Coherence Tomography (OCT) imaging techniques.

Subjects and Methods: A prospective non- randomized cross sectional study of 90 eyes of 58 Saudi Diabetic Retinopathy (DR) patients (36 Males and 22 Females aged from 22-80 years old) were examined using diagnostic UWFA (Optos 200Tx imaging system), in the late phase of Fluorescein Angiography (FA) to assess the presence of PRI. Based on OCT and early/ mid phases of FA using Topcon camera, patients were classified as either having DME or not. Chi-square test was used to assess the correlation between DME and PRI. The level of statistical significance was set at (P= 0.05).

Results: This study included 90 eyes from 58 DR patients (36 Males and 22 Females) who underwent diagnostic UWFA. DME was detected in 69 eyes (76.7%) of those eyes. Eyes diagnosed with DME were divided into four types: diffuse 36 eyes (40.0%); focal 23 eyes (25.6%); combined 6 eyes (6.7%) and cystoids, 4 eyes (4.4%). Out of these 90 eyes, 63 (70.0%) demonstrated PRI.