Vaccines for Varicella and Herpes Zoster - A Review

Review Article

Austin J Dermatolog. 2016; 3(4): 1060.

Vaccines for Varicella and Herpes Zoster - A Review

Puri N*

Department of Dermatology and Venereology, G.G.S. Medical College & Hospital, India

*Corresponding author: Neerja Puri, Department of Dermatology and Venereology, Consultant Dermatologist, Punjab Health Systems Corporation, G.G.S. Medical College & Hospital, Faridkot. 151203. Punjab, India

Received: September 06, 2016; Accepted: November 14, 2016; Published: November 15, 2016

Abstract

Introduction: Both varicella and herpes zoster are caused by varicella zoster virus. Vaccine for both the viral diseases is given to prevent the severe episodes of chicken pox and herpes zoster.

Discussion: Vaccine used for prevention of herpes zoster uses the same attenuated virus as in varicella vaccination but at much higher titres. The efficacy and complications of both the vaccines would be discussed.

Keywords: Varicella; Herpes zoster; Vaccine; Immunization; Prevention; Post herpetic neuralgia

Background

Varicella or chicken pox is the primary infection with varicella zoster virus. In tropical countries, 90% of cases of varicella occur in children below 10 years of age (Figure 1) whereas in temperate countries it occurs more in adults. Patients are infectious five days before and 5-6 days after eruption. Herpes zoster is caused by reactivation of varicella zoster virus after primary infection or vaccination [1]. Varicella zoster virus remains latent in the sensory dorsal root ganglion cells. During periods of immunosuppression, the virus travels down the sensory nerve into the skin [2].

Citation: Puri N. Vaccines for Varicella and Herpes Zoster - A Review. Austin J Dermatolog. 2016; 3(4): 1060. ISSN:2381-9197