Clinical Image
Ann Hematol Oncol. 2014;1(2): 1009.
A Rare Form of Mycobacterium Avium Infection in A Patient Treated for A Chronic Lymphocytic Leukemia
Marchand T1,2*, Revest M3,4 and Lamy T1,2
1Department of Clinical Hematology, Rennes University Hospital, France
2INSERM UMR 917, Université Rennes 1, France
3Infectious Disease and Intensive Care Unit, Rennes University Hospital, France
4CIC INSERM 0203, Université Rennes 1, France
*Corresponding author: Tony Marchand, Department of Clinical Hematology. Rennes University Hospital, 2, rue Henri Le Guiloux, 35033 Rennes Cedex 9, France
Received: November 18, 2014; Accepted: November 21, 2014; Published: November 24, 2014
Clinical Image
A 73 years old woman, known for a chronic lymphocytic leukemia previously treated by 3 chemotherapy lines presented a painful swelling of the right lower limb after a fall. Physical examination did not find lymphadenopathy in an a febrile patient. Magnetic Resonance Imaging (MRI) revealed a collection of the postero-internal muscle compartment of the right thigh. The hypothesis of a hematoma was made and analgesics prescribed. Six months later, patient had persistent pain. The control MRI revealed a major increased in the volume of the collection measuring 10 x 8 x 20 cm with a fatty infiltration (Panel A and B). A surgical washing was performed. Culture grew Mycobacterium avium. Treatment consisted of oral antibiotics (clarithromycine, ethambutol and Rifabutine) and was followed by a rapid clinical improvement. Nontuberculous mycobacterial infections usually affected immunocompromised host. Diagnosis of this rare kind of infection is often difficult and requires clinical, radiological and microbiological expertise.
Panel A and B: Magnetic resonance imaging of the right thigh showing the
voluminous abscess involving the internal compartment of the thigh.
Download PDF