Case Report
Ann Surg Perioper Care. 2022; 8(1): 1055.
Perioperative Care of Mega Obese (BMI >70) Patients Undergoing Bariatric Surgery
Philip S1*, Mathai AS2, Mathew T3 and Finny P4
1Department of Gastroenterology Hepatology and Transplantation, Believers Church Medical College Hospital, India
2Department of Anaesthesia, , Believers Church Medical College Hospital, India
3Department of Physical Medicine and Rehabilitation, Believers Church Medical College Hospital, India
4Department of Endocrinology, Believers Church Medical College Hospital, India
*Corresponding author: Philip S Department of Gastroenterology Hepatology and Transplantation, Believers Church Medical College Hospital, Tiruvalla, Kerala, India.
Received: November 15, 2022; Accepted: December 28, 2022; Published: January 04, 2023
Abstract
The prevalence of obesity in the world has recently soared due to changes in life style habits. This report describes the perioperative management of a patient with one of the highest Body mass index ever reported from Asia who underwent bariatric surgery. The patient, a 32 year gentleman with a Body Mass Index 74 had Mega Obesity according to standard classification. This article discusses the management of perioperative challenges faced in mega obese patients.
Keywords: Bariatric Surgery; Perioperative Care; Mega Obesity; Super-Super Obesity
Case Report
A 32 year old gentleman, an IT professional presented with significantly poor quality of life due to morbid obesity and its associated comorbidities. His weight was 241 kg and BMI74 .He was classified as mega obese which is the highest grade of obesity as per classification [1]. He had rapidly gained 91kg over a few years due to limited mobility of Covid lockdown and later work from home along with poor dietary habits.
Preoperative Assessment
On presentation he was comprehensively assessed by a multidisciplinary team consisting of an endocrinologist, pulmonologist, cardiologist, physiatrist, anaesthetist, dietician, psychologist and gastrointestinal surgeons. An interdisciplinary meeting was convened which also included the bio medical engineering department, operating room technicians and nurses to assess possible challenges in the perioperative period. He was admitted 4 weeks prior to surgery for evaluation. In addition to routine preoperative tests for ASA 3 patients he underwent a coronary angiogram, sleep study and hormonal evaluation. He was diagnosed to have Type 2 diabetes mellitus, non-alcoholic steatohepatitis and hypogonadotrophic hypogonadism. Cardiology evaluation was normal. Pulmonary evaluation revealed obstructive sleep apnoea and obesity – hypoventilation syndrome. After preoperative counselling for the patient and family and explaining the risks and benefits associated with surgery in such mega obese patients he was planned for bariatric surgery in the form of a Laparoscopic Sleeve Gastrectomy (LSG).
Perioperative Setup and Care
As mentioned, he was admitted 4 weeks prior to the surgery. A personalised tailored approach to the patient was adopted. This included preoperative graded cardio respiratory conditioning, individualised dietary regimes, and deep vein thrombosis prophylaxis besides incentive spirometry. He was shifted daily to the physiotherapy and rehabilitation department for exercises to improve physiological reserve. Overnight non invasive ventilation was initiated 4 weeks prior to surgery [2]. He had significant improvement in exercise capacity, improved sleep cycles, as well as weight reduction (down to 229Kg) by the end of 4 weeks. A mock drill was conducted to ascertain ability to assume supine ramp position for intubation, manoeuvrability on the extra weight bearing patient shifter as well the as the movement of the extra-large bariatric bed through OT doors and corridors. A safety briefing including proper positioning, appropriate equipment, anaesthetic approach, specific surgical procedure and plan for postoperative care, including airway respiratory support, ultimate recovery location (ICU) were rehearsed with the entire operating room personnel and the patient. Load bearing capacity of hospital furniture planned for use was reviewed including the toilet seats and ICU beds. Individual drug dosages were titrated according to their pharmacokinetic and pharmacodynamic properties especially its fat deposition by the clinical pharmacist. Advice from two pioneers in bariatric surgery in the world too was sought in planning.
After induction of general anaesthesia, lung protective ventilation strategies were adopted including recruitment manoeuvres during induction and on starting pneumoperitoneum. Specifically, high precision piston ventilator, TOF (Train of Four) monitoring, desflurane and opiod sparing analgesics were used to ensure smooth and early extubation at the end of surgery. Extra large bariatric cuffs were used for mechanical deep vein thrombosis prophylaxis.
Regarding surgical challenges, two operating tables were strapped together and extra large tables could not accommodate the patient. These tables were moved synchronously during surgery for proper positioning. Specially designed straps were applied to prevent patient slipping off table and leg split position given. (Figure 1). Pneumoperitoneum pressure was kept at 18 mmHg. Extra Long bariatric ports and instruments were used [3,4]. The patient was extubated on table to a non invasive ventilator. Graded intensive physiotherapy and orals was started from day 1. His liver function tests and sugars normalised within a few days. He was restarted on graded cardio respiratory conditioning. He had an uneventful recovery (Clavien- Dindo classification Grade 1) [5]. He has completed one year of follow up with monitoring of nutritional and electrolyte parameters and lost 60 kg.
Discussion
The prevalence of obesity has increased has soared recently. This may be partly attributed to decreased physical activity secondary to work from home culture. These changes in life style may be in place for a long time [6]. Therefore it is imperative that hospitals become accustomed to dealing with morbidly obese patients in the coming days. This discussion describes the additional perioperative challenges we faced in doing surgery on a mega obese patient (BMI >70).
Preoperative cardio respiratory conditioning of the patient by a multidisciplinary team is of paramount importance in such patients for optimum results. A standardised bariatric surgery work up protocol is useful to minimise errors. Due to transport issues for such patients, prep evaluation is best done in an inpatient setting. Most patients have obstructive hypoventilation syndrome requiring titrated non invasive ventilation preoperatively. Physiotherapy and strict diet for at least 4 weeks preoperatively is important by helping the patient to tolerate surgery better and also reduces the size of the liver, facilitating its retraction. The large friable fatty liver overlying the gastroesophageal junction is a major factor making adequate resection of fundus of stomach difficult. Obesity being a hyper coagulable condition both mechanical and pharmacological DVT prophylaxis are usually used. A detailed psychology evaluation and consultation will prime the patient and prevent recidivism.
The infrastructure requires wider stronger patient seats, customised dressing gowns and footwear, floor mounted or reinforced toilets , bariatric beds, bariatric DVT and BP cuffs, portable doppler for placement of vascular lines, bariatric surgery OT tables (two OT tables strapped together in this case), patient transfer equipment including OT shifters and wheel chairs. Radiological investigations have limitations in morbid obesity. Obesity will impair the quality of plain radiographs. To overcome the attenuation of the signal by excess subcutaneous adipose tissue lowest frequency probe was used for USG. Both CT and MRI gantry usually have weight limit of 180 kg only .This fact would be important if there is a postoperative complication like leak or pulmonary embolism as radiological investigation wouldn’t be possible unless CT/MRI machine with larger weight limit is available. The economic implications of hospitals treating an increasing number of obese patients are extensive as expanded weight capacity equipment typically costs 25%-100% more than standard items.
Bariatric operating instruments, ports, scopes and liver retractors are available on request from manufacturers. Android distribution of fat in peritoneal cavity as a whole limits visualisation of upper abdomen. Therefore any amount of bleed significantly reduces the visibility in such patients. Hence meticulous dissection to have a bloodless surgical field is crucial.
Postoperatively such patients develop a telectasis rapidly. Hence it is important to start non invasive ventilation immediately after extubation. Early mobilisation and starting of graded physiotherapy and progressively increasing nutrition will aid a quicker recovery. Since there are higher chances of morbidity and mortality, protocols should be in place to diagnose and treat complications early especially if there are limitations on radiological and endoscopic facilities.
As demonstrated in this report, with adequate preparation and multidisciplinary care, mega obese patients can be operated with good perioperative outcome. This would be especially relevant in the present era with a rising prevalence of obesity.
References
- De Pinieux G, Karanian M, Le Loarer F, Le Guellec S, Chabaud S, Terrier P, et al. Nationwide incidence of sarcomas and connective tissue tumors of intermediate malignancy over four years using an expert pathology review network. PLoS One. 2021; 16: e0246958.
- Kim JM, Choi Y La, Kim YJ, Park HK. Comparison and evaluation of risk factors for meningeal, pleural, and extrapleural solitary fibrous tumors: A clinicopathological study of 92 cases confirmed by STAT6 immunohistochemical staining. Pathol - Res Pract. 2017; 213: 619–25.
- Ronchi A, Cozzolino I, Zito Marino F, Accardo M, Montella M, Panarese I, et al. Extrapleural solitary fibrous tumor: A distinct entity from pleural solitary fibrous tumor. An update on clinical, molecular and diagnostic features. Ann Diagn Pathol. 2018; 34: 142–50..
- Guglielmi A, Frameglia M, Iuzzolino P, Martignoni G, De Manzoni G, Laterza E, et al. Solitary fibrous tumor of the liver with CD 34 positivity and hypoglycemia. J Hepatobiliary Pancreat Surg. 1998; 5: 212–6.
- Vennarecci G, Ettorre GM, Giovannelli L, del Nonno F, Perracchio L, Visca P, et al. Solitary fibrous tumor of the liver. J Hepatobiliary Pancreat Surg. 2005; 12: 341–4.
- Chithriki M, Jaibaji M, Vandermolen R. Solitary fibrous tumor of the liver with presenting symptoms of hypoglycemic coma. Am Surg. 2004; 70: 291–3.
- Chun HJ, Byun JY, Jung SE, Kim KH, Shinn KS. Benign solitary fibrous tumour of the pre-sacral space: MRI findings. Br J Radiol. 1998; 71: 677–9.
- Kinoshita T, Ishii K, Higashiiwai H, Naganuma H. Malignant Solitary Fibrous Tumour of the Peritoneum: Case Reports. Clin Radiol. 2000; 55: 157–60.
- De Bernardi A, Dufresne A, Mishellany F, Blay JY, Ray-Coquard I, Brahmi M. Novel Therapeutic Options for Solitary Fibrous Tumor: Antiangiogenic Therapy and Beyond. Cancers (Basel). 2022; 14: 1064.
- Kallen ME, Hornick JL. The 2020 WHO classification: What’s new in soft tissue tumor pathology? Am J Surg Pathol. 2021; 45: 1–23.
- Yoshida A, Tsuta K, Ohno M, Yoshida M, Narita Y, Kawai A, et al. STAT6 immunohistochemistry is helpful in the diagnosis of solitary fibrous tumors. Am J Surg Pathol. 2014; 38: 552–9.
- Geramizadeh B, Marzban M, Churg A. Role of immunohistochemistry in the diagnosis of solitary fibrous Tumor, a review. Iranian Journal of Pathology. 2016; 11: 195–203.
- Zafar H, Takimoto CH, Weiss G. Doege-Potter syndrome. Med Oncol. 2003; 20: 403–7.
- Steigen SE, Schaeffer DF, West RB, Nielsen TO. Expression of insulin-like growth factor 2 in mesenchymal neoplasms. Mod Pathol. 2009; 22: 914–21.
- Le Roith D. Tumor-Induced Hypoglycemia. N Engl J Med. 2008; 341: 757–8.
- Haaga JR. CT and MRI of the Whole Body. 5th ed. 2008; 1: 2734.
- Stacchiotti S, Libertini M, Negri T, Palassini E, Gronchi A, Fatigoni S, et al. Response to chemotherapy of solitary fibrous tumour: A retrospective study. Eur J Cancer. 2013; 49: 2376–83.
- Salas S, Resseguier N, Blay JY, Le Cesne A, Italiano A, Chevreau C, et al. Prediction of local and metastatic recurrence in solitary fibrous tumor: construction of a risk calculator in a multicenter cohort from the French Sarcoma Group (FSG) database. Ann Oncol Off J Eur Soc Med Oncol. 2017; 28: 1979–87.
- England DM, Hochholzer L, McCarthy MJ. Localized benign and malignant fibrous tumors of the pleura. A clinicopathologic review of 223 cases. Am J Surg Pathol. 1989; 13: 640–58.
- Baldi GG, Stacchiotti S, Mauro V, Dei Tos AP, Gronchi A, Pastorino U, et al. Solitary fibrous tumor of all sites: outcome of late recurrences in 14 patients. Clin Sarcoma Res. 2013; 3: 1–7.
- Gholami S, Cassidy MR, Kirane A, Kuk D, Zanchelli B, Antonescu CR, et al. Size and Location are the Most Important Risk Factors for Malignant Behavior in Resected Solitary Fibrous Tumors. Ann Surg Oncol. 2017; 24: 3865–71.
- Demicco EG, Wagner MJ, Maki RG, Gupta V, Iofin I, Lazar AJ, et al. Risk assessment in solitary fibrous tumors: validation and refinement of a risk stratification model. Mod Pathol. 2017; 30: 1433–42.
- Robinson LA. Solitary fibrous tumor of the pleura. Cancer Control. 2006; 13: 264–9.