A Challenging Task: Prevention and Control of Cancer in India

Review Article

J Bacteriol Mycol. 2024; 11(2): 1221.

A Challenging Task: Prevention and Control of Cancer in India

J Cyril Kanmony*

Professor Emeritus, PG & Research Centre, Department of Economics, Scott Christian College (Autonomous), India

*Corresponding author: J Cyril Kanmony, Professor Emeritus, PG & Research Centre, Department of Economics, Scott Christian College (Autonomous), Nagercoil–629003, India. Email: cyrilkanmony@ymail.com

Received: October 10, 2024; Accepted: October 30, 2024 Published: November 06, 2024

Abstract

Apart from disability and injury and other diseases, including maternal, neonatal, and nutritional diseases, there are Communicable Diseases (CDs) and Non-Communicable Diseases (NCDs) that cause mortalities. Globally, one of the major health threats under NCDs is cancer, which causes millions of deaths every year. While the occurrence of CDs is slowly increasing, the occurrence of NCDs is increasing very fast. There are many risk factors for cancer. Broadly, they are classified into three groups: behavioral risks, environmental risks, and metabolic risks. Behavioral risks include dietary risk, tobacco consumption, high drug and alcohol use, genital hygiene, etc. Environmental risks refer to risks related to air pollution, unsafe water and sanitation, occupational risks, etc., while metabolic risks are those risks caused by high blood pressure, high plasma glucose, high LDL cholesterol, high body mass index, etc. In India, both cancer cases and cancer-related deaths are increasing fast. But public facilities available for cancer screening and treatment are few and far between. Hence people opt for private hospitals, where service is good but cost is very high, and so Out-Of-Pocket Expenditure (OOPE) is very high. Most of the patients affected by cancer are men, aged between 50 and 70 and belonging to a middle- or lowincome group. These views are supported by the primary data collected from Kanniyakumari district, Tamil Nadu, India. Of the surveyed patients, 56.67% are men and in the age group of 50–70 years, and 76.67% of cancer patients belong to either a low- or middle-income group. The OOPE is as much as 65.16%. A few suggestions are given to make people feel relieved from the hazards of cancer. However, under the prevailing situations, the prevention and control of cancer is a challenging task for the government of India.

Keywords: Non-Communicable Diseases; Communicable Diseases; Cancer incidence rates; Environmental risks; Out-of-pocket-expenditure; Public healthcare facilities.

Introdution

Cancer is one of the major causes of a few million mortalities in the world. Mortalities occur due to two reasons. They are morbidities and accidents. Accidents are almost unavoidable. Major morbidities or diseases may be of two types. They are Communicable Diseases (CDs) and Non-Communicable Diseases (NCDs) apart from disability and injury and other diseases including maternal, neonatal, and nutritional diseases [17,18]. Communicable diseases are those diseases that spread through the causative/infective organisms or pathogens, which are carried from one person to another directly or indirectly. Hence, they are also called infectious diseases. Due to various efforts taken by world countries and medical advancements, the seriousness of many CDs is slowly disappearing and less concentration is given on these CDs. Even COVID-19 itself is under control, and so no government has taken even the counting of patients infected by the Corona virus for the lost three or four years. Diseases like malaria and tuberculosis are almost on the verge of disappearance. Diseases like polio are completely eradicated. Poliovirus type 2 was certified eradicated even in 2015, and there has been no detection of poliovirus type 3 since 2012 and it was certified eradicated in 2019 [29]. But at the same time, some diseases like monkey pox, amoeba, dengue, niba, and zika affect people here and there frequently.

The above-mentioned fact is true to India also. Because of various measures taken by healthcare departments and central and state governments, the occurrence of CDs in India is controlled significantly. However, the occurrence of NCDs is increasing without much control. The prevalence of CDs increased only by 1.88 times between 1995 and 2018, while the prevalence of NCDs has increased by 3.50 times in the same period-more than tripled [18]. Due to the increase in the prevalence of morbidities, mortalities related to them also increased between periods. In India, the total number of estimated deaths from all causes, including injuries, is 11.74 million in 2021. Of these, the total number of deaths due to communicable diseases, maternal, neonatal, and nutrition-related diseases is 3.69 million, and deaths due to the COVID-19 pandemic are 0.65 million. It is very sad to note that the deaths due to NCDs are 6.47 million. Of the total deaths related to NCDs, the maximum is contributed by cardiovascular diseases (2.87 million), and the second is by chronic respiratory diseases, numbering 1.33 million. The third most contributing factor to NCD-related deaths is cancer, consisting of 0.85 million deaths (13.21%) [17]. These figures speak volumes about the adverse impact of NCDs, particularly cancer, on people’s health. To emphasize the importance of prevention and control of cancer, every year the 4th of February is observed as ‘the World Cancer Day’ and the 1st of August as ‘the World Lung Cancer Day’.

Cancer is not a single disease. It is a group of diseases having almost similar characteristics, diagnosed on the basis of changes in cells, divided and subdivided, and multiplied in an inappropriate number. In other words, it refers to a changed status of a tissue or cell of any part of the body of a living being by forming a tumor, which has a different behavior from the ordinary cells. These cellular changes are called neoplasm, malignancy, oncogenes, neoplastics, etc. [14]. It means that cancer can affect not only human beings but also other living beings that have cells. Globally, cancer is a major health threat to human life after cardiovascular diseases [2], and the total number of cancer cases and cancer-related deaths are increasing continuously; cancer cases increased from 18.1 million in 2018 to 19.3 million in 2020. Cancer-related deaths mounted to 10 million in 2020 from 9.6 million in 2018 [24]. It is estimated that cancer cases increased to 20 million and deaths to 9.7 million in 2022, and the number of persons who are alive within five years after the positive diagnosis is 53.5 million [26]. Globally, among cancers, lung cancer tops the list with 2.5 million (12.4%), and breast cancer follows it with 2.3 million, i.e., 11.6%. The third common cancer is colorectal cancer, numbering 1.9 million cases (9.6%). In the same way, lung cancer is the top most contributor to total cancer-related deaths, with 1.8 million deaths (18.7%), and colorectal cancer occupies the second place with 0.90 million deaths, or 9.3%. The third place is occupied by deaths caused by liver cancer, 0.76 million, or 7.8%, and deaths due to breast cancer occupied the fourth place, 0.67 million deaths, or 6.9% of total cancer deaths [33]. The report also indicates that the total number of cancer cases in 2050 will be 35 million, an increase of 77%. In 91 countries out of 172 countries taken for discussion, cancer is the first or second leading cause of adult deaths, and in another 22 countries, it is the third or fourth cause of adult deaths [27].

In India also, the total number of cancer cases is continuously increasing; it is the second leading cause for adult deaths in urban areas and fourth in rural areas. In reality, the diagnosis of cancer started in India only in the 19th century, but it became a health burden in the 20th century [27]. The average number of cancer cases in India per year is 0.8 million, and at any given point in time there are at least 2.4 million cancer cases [30]. At present, India is considered ‘the Cancer Capital of the World’ [21,31]. In India, between 1990 and 2016, both cancer cases and cancer deaths had doubled (Dhilon et al., 2018) [24,27]. The total number of persons affected by cancer increases from 0.98 million in 2010 to 1.39 million in 2020 [14] and to an estimated number of 1.46 million in 2022. Deaths related to cancer were only 0.2 million persons in the 1950s, according to Pai and Khanolkar [27]. They show a sharp increase in the 21st century: 0.77 million in 2020 and 0.81 million in 2022 [3]. Like the global trend, lung cancer in India is rising very fast, and deaths related to lung cancer contribute about 10% of the total cancer-related deaths. In terms of total number of lung cancers, India occupies the fourth place among world countries with 81,000 cases and 75,000 (92.59%) deaths in 2022 [25]. The overall burden of cancers in India is expected to increase by 31.4% between 2005 and 2025 [18,24]. It is also noteworthy to indicate that the most affected persons are in the age group of 50-69 years [2]. But the great concern for medical fraternity is that there is a sharp increase in the occurrence of cancer cases among persons belonging to the age group of 15-39 [18]. All these mean that in India, cancer cases and cancerrelated deaths are increasing fast. However, in India, the contribution of each state to total cancer cases differs a lot. Uttar Pradesh has an estimated heavy load of 0.21 million cancer cases while the minimum load of just 496 cases is reported from Sikkim in 2020 [3]. As it is better to highlight states that are contributing the most to the total cancer cases and cancer-related deaths, data related to the top seven states are presented in the following table.