Leiomyoma of Oral Cavity in a Young Child

Case Report

Austin J Clin Case Rep. 2015;2(1): 1067.

Leiomyoma of Oral Cavity in a Young Child

Subramanya Sharma S1*, Ramakrishnan K2, Vijayalakshmi D2 and Saravanan C3

1Department of Oral & Maxillofacial Surgery, Adhiparasakthi Dental College & Hospital, India

2Department of Oral Pathology & Microbiology, Adhiparasakthi Dental College & Hospital, India

3Department of Oral & Maxillofacial Surgery, SRM Dental College & Hospital, India

*Corresponding author: Subramanya Sharma S, Department of Oral & Maxillofacial Surgery, Adhiparasakthi Dental College & Hospital, Melmaruvathur, Tamilnadu, India

Received: December 11, 2014; Accepted: March 23, 2015; Published: April 16, 2015


Leiomyoma is a slow-growing, benign tumor of smooth muscle origin presenting clinically as a soft tissue tumor. It occurs more commonly in the gastrointestinal tract, skin, uterus and the subcutaneous tissues. Oral leiomyomas are quite rare. Reported tumors have commonly presented in the lips, tongue, buccal mucosa, palate and mandible. Most of the reported cases are in the 4th and 5th decades of life with very few cases reported in paediatric age group. Most of the lesions are small, asymptomatic and present as a smooth elevated area with pigmentation. We present a case report of an 8-yearold Indian (Asian) boy with a large, exophytic mass in the lingual aspect of the mandible. The size, the site and the age at presentation makes this a rare case worth to be recorded.

Keywords: Smooth muscle; Leiomyoma; Immunohistochemistry


Leiomyoma is a benign neoplasm of smooth muscle origin. General absence of smooth muscles in the oral region makes it a rare tumor. Several histological variants described are; Solid Leiomyoma, vascular leiomyoma and Epithelioid variety [1,2]. Vascular leiomyoma, otherwise known as angiomyoma is the most common variant reported in the oral cavity [2,3]. Leiomyoma shows a male predilection of 1.4: 1. It usually presents itself around the 4th to 5th decades of life. The common oral sites are lips, tongue and buccal mucosa. Various other sites including the palate, gingiva and the mandible have been reported [4-6]. Incidence of malignant transformation has not been reported [1,2,7].

We report the case of a male child, who presented with an Oral Leiomyoma.

Case Presentation

An 8-year-old Indian (Asian) boy reported to the out-patient clinic of the Department of Oral & Maxillofacial Surgery with the complaint of a large mass on the lingual aspect of his right mandible in relation to the molar region. The lesion has been present since 6 months and has been growing gradually. It got traumatized frequently during mastication, associated with minor bleeding episodes.

Clinical examination revealed a painless, quite large, solitary, pedunculated, exophytic mass with an irregular, surface in the traumatized areas and other areas were pale pink in color (Figure 1). It measured about 3 x 4 cm in size extending anteriorly from the deciduous first molar to the retromolar area posteriorly on the right lingual aspect of alveolar mucosa and gingiva. Superiorly, the lesion extended to the line of occlusion and inferiorly upto the floor of mouth. Medially the lesion was adherent to the lingual aspect of mandible. The lesion was firm in consistency. No regional lymphadenopathy was evident. Differential diagnoses for the peripheral, oral exophytic lesion are Inflammatory Hyperplasias and peripheral benign mesenchymal tumors. An excisional biopsy was done and the specimen was sent to the Oral Pathology Department (Figure 2).