Effects of <em>Moringa Oleifera</em> Leaves on Hematological Indices in Humans

Research Article

Ann Hematol Oncol. 2016; 3(8): 1107.

Effects of Moringa Oleifera Leaves on Hematological Indices in Humans

Adegbite OA¹, Omolaso B², Seriki SA²* and Shatima C²

¹Centre for Infectious Diseases, Nigerian Army Reference Hospital, Nigeria

²Department of Human Physiology, College of Medicine Bingham University, Nigeria

*Corresponding author: Samuel A.Seriki, Department of Human Physiology, College of Medicine Bingham University, Karu, Nigeria

Received: July 28, 2016; Accepted: September 17, 2016; Published: September 19, 2016


Background: In recent times, attention has been drawn to the several beneficial effects of Moringa Oleifera. Its leaves have been known for its medicinal attributes. This is because of its richness in phytochemicals, antioxidants, vitamins, and proteins. It has been said to possess antitumor, anticancer, antiinflammatory, antibacterial, hepatorenal and hematopeotic activities. Several researches have adopted animal models to elicit these benefits. The current study is on the effect of powdered Moringa Oleifera leaves on hematological indices in human. The study investigates the widespread belief of the usefulness of Moringa Oleifera to human like it is to animals.

Method: Twenty (20) human subjects used for the research were grouped into two of ten (n=10) and given low and high doses of Moringa Oleifera (0.038 g/kg and 0.077 g/kg respectively) for 14 days (two weeks). Their blood samples were collected and analyzed before and after the two weeks.

Results: Results show significant improvement in platelet count in the group given low dose of the extract (p<0.05), but insignificant improvement in the group given high dose. Though there was increase in red cell count, it was not significant in both groups. White blood cell count insignificantly dropped in both groups.

Conclusion: Moringa Oleifera has hematopoietic activity in humans; it is especially beneficial to platelet count (when taken in low dose), and it is also beneficial to red blood cell formation (though not to a significant level). However, its immune enhancing benefit is less certain.

Keywords: Moringa Oleifera; Red Blood Cell; Platelet; White Blood Cell; Hemopoietin; Hematinic


Anemia is one of the major challenges in the developing countries. Its causes include malaria infection, bacterial and viral infections, worm infestation, pregnancy and other diseased conditions. Focus is therefore progressively on how to meet this blood demand posed by these conditions. Unlike in the past, attention is gradually shifting from blood transfusion, not only because of non-availability and nonaffordability, but also because of the many risks associated with it. Several options that have been explored include the use of parenteral iron, hematinic like iron and folic acid supplements. Attention has recently been paid to the use of natural herbs, which are more available and affordable.

Products from many plants are known to have some hematopoietic activities. Examples of these are garlic [1], Clerodendrumviolaceum leaves [2], Mangiferaindica [3], Telfairiaoccidentalis (Ugwu leaves). These have all been used to boost blood production by the body. Literatures are replete with evidences of their effectiveness.

Recently, attention has been drawn to several benefits of Moringa Oleifera, including its ability to enhance blood formation and boost the immune system. Other medicinal properties have also been ascribed to various parts of Moringa Oleifera. Almost every part of the plant: root, bark, gum, leaf, fruit (pods), flowers, seed and seed oil has been used for various ailments in medicine [4], including the treatment of inflammation and infectious diseases along with cardiovascular, gastrointestinal, hematological and hepato-renal disorders [5-8]. Acute intake of Moringa Oleifera leaves (Figure A) has been shown to lower blood pressure, body temperature and blood glucose level in human [9]. Most parts of the plant possess antimicrobial activity [10,11]. They are well known as good alternative for the treatment of diabetes mellitus [12-14], hepatotoxicity [15], rheumatism, venomous bites as well as for cardiac stimulation [16]. It is used for arthritis and