Bone Metastases from Prostate Cancer. What is the Role of Bone Scintigraphy in the Era of Choline PET/CT?

Letter to the Editor

J Mol Biol & Mol Imaging. 2014;1(1): 1.

Bone Metastases from Prostate Cancer. What is the Role of Bone Scintigraphy in the Era of Choline PET/CT?

Garcia JR*, Mañe S, Soler M, Moragas M, Llinares E and Riera E

CETIR Unitat PET, Esplugues Llobregat, Barcelona, Spain

*Corresponding author: Garcia JR, Barcelona Area, Spain Hospital & Health Care, CETIR Unitat PET. Esplugues Llobregat, Barcelona, Spain

Received: July 07, 2014; Accepted: July 07, 2014; Published: July 09, 2014

We presented a patient with prostate cancer treated with prostatectomy and lymphadenectomy who present rising PSA (3,7 ng/ml) with negative pelvic-MRI and abdominal-CT.

Whole body 11C-Choline PET/CT showed solitary tracer uptake in left supra-acetabular region. Axial fused PET/CT and a CT image allows locating this uptake in medullary region without morphological abnormality.

Planar bone whole body scintigraphy showed spondyloarthropathy dorsal signs without focal tracer uptakes suggesting bone metastases. Moreover distribution of the tracer in pelvis was symmetrical.

However, due to 11C-Choline uptake in left supra-acetabular region pelvic SPECT/CT was performed. Coronal and axial SPECT/ CT detected focal osteogenic uptake in medullary region. Guided biopsy confirmed bone metastases.

Bone Scintigraphy has traditionally been considered the most sensitive method for detection of bone metastases, especially blast injuries, the most common in prostate cancer.

Citation: Garcia JR, Mañe S, Soler M, Moragas M, Llinares E and Riera E. Bone Metastases from Prostate Cancer. What is the Role of Bone Scintigraphy in the Era of Choline PET/CT?. J Mol Biol & Mol Imaging. 2014;1(1): 1. ISSN:2471-0237