An Unusual Adrenal Tumor not to be Ignored!

Case Report

Ann Carcinog. 2019; 4(1): 1016.

An Unusual Adrenal Tumor not to be Ignored!

Tbouda M1*, Toufga Z2, Belhabib S1, Zouaidia F1, Znati K1, Jahid A1 and Bernoussi Z1

¹Department of Anatomical Pathology, Ibn Sina Hospital, Morocco

²Department of Radiology, Ibn Sina Hospital, Morocco

*Corresponding author: Tbouda M, Department of Anatomical Pathology, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Hôpital Militaire Mohamed V, Rabat, Morocco

Received: February 19, 2019; Accepted: March 22, 2019; Published: March 29, 2019


Adrenal tumors are dominated by epithelial tumors. Mesenchymal tumors are rare. Among these tumors is Leiomyosarcoma (LS), which is extremely rare. It originates from the muscle cells of the muscular is of the adrenal veins. Immunocompromised individuals are the most susceptible to this type of tumor. We report a case of LS in a 17-year-old patient presenting for an abdominal mass in a context of general deterioration. Imaging had suspected the diagnosis of a malignant adrenal tumor. Laparoscopic surgical resection was successfully performed. Clinical and radiological control was performed with a follow-up of 12 months.

A rare and aggressive tumor that most often requires radical surgery sometimes extended to neighboring organs. Chemotherapy and radiotherapy are indicated in case of contraindication to surgery.

Keywords: Adrenal; Tumor; Leiomyosarcoma; Histology


LS: Leiomyosarcoma; CT: Tomography


Adrenal leiomyosarcoma is a rare tumor. Its frequency does not exceed 50 cases reported in the literature [1]. Its etiology is unknown, however, some authors estimate its high incidence in the population of individuals infected with HIV or Epstein-Barr virus [2]. It is an aggressive tumor that only radical surgery can improve survival. Chemotherapy and radiotherapy only indicated in case of unresectable and metastatic tumor [2]. We report here a case of leiomyosarcoma in a young subject, while describing the diagnostic circumstances and the therapeutic approach, while going through a review of the literature.

Case Report

This is a 49-year-old patient with no particular history who consulted for a progressive increase in the abdomen, in a context of general deterioration. The clinical examination finds a conscientious, afebrile patient with impaired facies. The abdominal examination shows a mass of the right flank, deep, painless. An ultrasound was performed showing a hyperechoic mass with hypoechoic areas at the right renal area. Completed by Computed Tomography (CT), the mass appeared poorly limited, heterogeneously enhanced after injection of contrast medium including vascular structures with ipsilateral renal pedicle extension and perirenal fat infiltration measuring 22×7 cm (Figure 1,2). The patient was hospitalized in the urology ward. A biological tests was carried out without particularities and including an HIV serology which was negative. Surgical resection of the tumor laparotomically has been successfully performed.