MR Findings of Primary Female Genital Tract Lymphoma: Cases Report and Literature Review

Case Series

Austin J Radiol. 2015;2(1): 1010.

MR Findings of Primary Female Genital Tract Lymphoma: Cases Report and Literature Review

He Zhang*

Department of Radiology, Fudan University, China

*Corresponding author: He Zhang, Department of Radiology, Obstetrics and Gynecology Hospital, Fudan University, No.419, Fangxie, Shanghai, P.R. China

Received: January 07, 2015; Accepted: February 17,, 2015; Published: February 18,, 2015


Primary female genital tract lymphoma is a rare etiology with extremely rare occurrence. Imaging findings of primary female genital tract lymphoma are mostly reported in case report. Here, we reported three cases in our single institution with focus on the conventional MRI and Diffusion-Weighted Imaging (DWI) findings. In this cohort case series, there were no additional abnormal findings in other organs except in female genital tract. Lymphadenopathy was observed in one case and tumor extended beyond the uterus was observed in another case. The tumor enhancement and DWI findings were not different from other female malignant tumors. The final histological diagnosis will be needed to determine the etiology of disease.


Primary lymphoma involving female genital tract is extremely rare. It is reported that the incidence is about 0.2 - 1.1% of all primary extranodal lymphoma [1]. Primary non-Hodgkin lymphoma of ovary accounts for ~1.5% of all ovarian tumors. Most of primary lymphoma in gynecological tract has been published as “cases report” type when searched the database on Medline [2-4]. Owing to the capability of multi-planar imaging and better soft tissues resolution, Magnetic Resonance Imaging (MRI) has its great advantages in characterizing gynecological tumors [5]. However, only few studies described the imaging findings of lymphoma of ovary and uterus at MRI [6-8]. In this short report, we reported three patients in our single institution with pathologically proved primary non-Hodgkin lymphomas of ovary and uterus in our institution. All of them underwent full MRI examinations before surgery.

Case 1

A 31-year-old woman presented with 01 month history of pelvic mass and abdominal distension. There were no vaginal discharge and bleeding. No other disease history has been recorded. The patient had a MRI scan before the surgery. On MRI, there was tubal mass along the surface of loop of small intestine (Figure 1). The mass appeared solid without clear margin with the surrounding tissues. The tumor displayed the intermediate signals on both T1WI (Figure 1A) and T2WI (Figure 1B) images and slightly high signals on DWI images (Figure 1C). On contrast-enhanced images, the mass displayed mild enhancement (Figure 1D). Pelvic images did not show free fluid or lymphadenopathy. The patient underwent laparotomy one week later. The gross findings revealed that the right ovary obviously enlarged in the size of 12×9×9 cm, which displayed as a gray, fragile mass with some necrotic sis areas in it. The final histological diagnosis was the B - cell lymphoma. On immunohistological analysis, the mass tested strong positive for CD10 antibody, mild positive for Ki67 and P53.