Recently Published Articles

Nov 23, 2017

Annals of Hematology & Oncology

Platelet Function and Bleeding Tendency in Patients under Ibrutinib Therapy

Abstract: Background: Ibrutinib is a first-generation covalent Bruton's kinase (BTK) inhibitor approved for the treatment of mantle-cell lymphoma (MCL), CLL, and Waldenstrom macroglobulinemia (WM). BTK is expressed on platelets and is...

Nov 23, 2017

Annals of Hematology & Oncology

Central Nervous System Localisation of Multiple Myeloma

Abstract: An 80-year-old woman presented to the emergency department with diffuse skeletal pain. She had a history of symptomatic multiple myeloma (MM) for which she had been treated with melphalan,...

Nov 23, 2017

Journal of Bacteriology and Mycology

Inflammatory Tinea Manuum due to Trichophyton Erinacei from a Hedgehog: A Case Report and Review of the Literature

Abstract: There have been an increasing number of reports of hedgehog related zoonotic diseases, which is reflective of the growing popularity of hedgehogs as exotic household pets. We present a case of an acute inflammatory tinea...

Nov 22, 2017

Austin Journal of Neurological Disorders & Epilepsy

A Systematic Approach for Identifying Shared-Mechanisms in Epilepsy and Its Comorbidities

Abstract: Cross-sectional epidemiologic studies have shown that the incidence of several nervous system diseases is more frequent in epilepsy patients than in the general population. Some comorbidities (e.g., Alzheimer's disease and Parkinson's disease)...

Nov 22, 2017

Physical Medicine and Rehabilitation - International

Oxidants, Antioxidants, and Delayed Language Correlations in Children with Autism

Abstract: Autism is complexes behaviorally known as neurodevelopmental disorder characterized by significant deterioration in social interaction, mental abilities language development and other communicative abilities...

Nov 22, 2017

Annals of Mutagenesis

Thymidylate Depletion Stimulates Homologous Recombination by UNG1-Dependent and UNG1- Independent Mechanisms in Saccharomyces cerevisiae

Abstract: Folate depletion increases the incidence of birth defects and triggers chromosomal breakage and homologous recombination. Inadequate levels of folates alter nucleotide balance by reducing thymidylate, leading to uracil...

Nov 22, 2017

Austin Hematology

Dominant Hereditary Essential Thrombocythemia Caused by Germline TPO Mutation Complicated by Secondary Myelofibrosis

Abstract: An activating mutation in the TPO gene caused dominant Hereditary Essential Thrombocythemia (HET) by the demonstration of the co-segregation of G to C transversion in the splice donor site...

Nov 21, 2017

Journal of Family Medicine

A Case of Refractory Pulmonary Coccidioidomycosis Successfully Treated with Posaconazole Therapy

Abstract: Coccidioidomycosis is an endemic fungal infection caused by the inhalation of the spores of Coccidioides species. Patients with underlying immunosuppressive illness can contract chronic or disseminated disease which...

Nov 21, 2017

Journal of Family Medicine

Depression, Anxiety and Burnout Syndrome in Medical Residents of Family Medicine in Tijuana, Mexico

Abstract: Background: Medical residents face constant processes of adaptation and learning; whose personal, educational and social implications can lead to serious mental disorders. Research reports prevalence of Burnout syndrome...

Nov 21, 2017

Austin Journal of Sleep Disorders

Characterizing the Sleep Disordered Breathing in Neuromuscular Diseases - Beyond the Polysomnography

Abstract: The development of chronic respiratory failure is the major problem in Neuromuscular Diseases (NMD), leading to increased morbidity and mortality, and their first signals are exhibit during the sleep...

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